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There were close NFL spreads for almost every game in Week 4, but that is not the case with the Week 5 NFL schedule. Caesars Sportsbook currently has six teams favored by at least one touchdown in the latest Week 5 NFL odds, including Buffalo as a 14-point favorite against Pittsburgh. The Bills have already blown out the Rams and Titans this season, so should you have faith in them when you make your Week 5 NFL office pool picks? Which other teams should you back with your Week 5 NFL confidence pool picks? Before you make your Week 5 NFL pick’em predictions, you need to see the Week 5 NFL football pool picks from SportsLine’s proven model.
The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 5 of the 2022 NFL season on an incredible 139-103 run on top-rated NFL picks that dates back to the 2017 season.
More importantly for NFL confidence pool players, the model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.
Now, the model has simulated the entire Week 5 NFL schedule 10,000 times and generated its optimal NFL pick’em plays. Go to SportsLine to see them now.
Top Week 5 NFL office pool predictions
One of the top Week 5 NFL predictions from the model: The Jaguars get a comfortable win as 7-point home favorites against Houston. Jacksonville opened as a 3.5-point favorite, but the early betting action has driven the line up by nearly five points. The Jaguars are returning home after playing consecutive road games against the Chargers and Eagles, splitting those contests. Their lone home game this season resulted in a 24-0 win over Indianapolis in Week 2.
Quarterback Trevor Lawrence has completed 65.7% of his passes for 946 yards and eight touchdowns, with wide receiver Christian Kirk hauling in 20 receptions for 327 yards and three scores. Houston is on a three-game losing skid following a 34-24 loss to the Chargers last week. Jacksonville blew out Los Angeles two weeks ago and is prepared to do the same against the Texans this week.
SportsLine’s model projects Lawrence to throw for more than 270 yards and two touchdowns, while Houston quarterback Davis Mills is throwing for less than 220 yards and one touchdown. Jacksonville is winning in well over 70% of simulations. See the rest of the model’s Week 5 NFL pool picks here.
How to make Week 5 NFL office pool picks
The model also made the call on every other Week 5 NFL game and has strong picks for potentially close matchups like Browns vs. Chargers and Patriots vs. Lions. It’s also calling for several big favorites to struggle more than expected and several shocking teams to hang tough. You can only see all of the model’s NFL pool picks here.
So who should you pick in every Week 5 NFL game? And which underdogs should you back? Visit SportsLine now to get optimal NFL office pool picks, all from the advanced computer model that has ranked in the top 10 on straight-up picks four of the last six years and went an outstanding 139-103 on top-ranked picks against the spread since 2017.
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