The Parramatta Eels host the Canterbury Bulldogs in a blockbuster clash at CommBank Stadium.
The Eels welcome back star halfback Mitchell Moses with Jacob Arthur dropping out of the side.
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Baily Simonsson is bidding to return from a hamstring injury from the reserves, which would see Waqa Blake shift to the centres and Tom Opacic drop out.
The Bulldogs welcome back enforcers Tevita Pangai Jr and Luke Thompson on the bench, with Chris Patolo and Jackson Topine dropping out.
The seventh placed Eels desperately need to win to keep their slim top four hopes alive, while the Bulldogs are trying to avoid the bottom four against their arch rivals.
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