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    Home»Sports»Week 10 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay pays out 25-1
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    Week 10 NFL picks, odds, 2022 best bets from advanced model: This five-way football parlay pays out 25-1

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    The Detroit Lions will try to build off their second win of the season when they face the Chicago Bears during the Week 10 NFL schedule on Sunday. The Lions, who had not won a game since Week 2 against Washington, picked up a 15-9 win against Green Bay as four-point underdogs last week. They are three-point underdogs against the Bears in the latest Week 10 NFL odds at Caesars Sportsbook. Should you back the Lions with your Week 10 NFL bets? Philadelphia, the league’s lone unbeaten team, will try to remain perfect when it faces Washington on Monday. The Eagles are 10.5-point favorites in the Week 10 NFL spreads, while the over/under is 44.5. Which Week 10 NFL lines should you target with your Week 10 NFL bets? Before you make any Week 10 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.

    The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 of the 2022 NFL season on an incredible 151-108 run on top-rated NFL picks that dates back to the 2017 season.

    The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

    Now, the model has locked in five confident NFL best bets for Week 10. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 10 NFL picks at SportsLine.

    Top Week 10 NFL picks

    After simulating every game 10,000 times, the model is high on the Tennessee Titans (-3) to cover the spread against the Denver Broncos. Tennessee is coming off an overtime loss to Kansas City on Sunday, but has still won five of its last six games. The Titans are led by star running back Derrick Henry, who has rushed for 870 yards and nine touchdowns, averaging 4.7 yards per carry.

    He will face a Denver defense that allowed 144 rushing yards to Las Vegas running back Josh Jacobs in October. The Broncos have also been one of the worst offensive teams this season, so they could have trouble matching Tennessee blow for blow. SportsLine’s model has Henry rushing for nearly 100 yards and a touchdown on Sunday, one reason why the Titans are covering the spread almost 60% of the time. See which other NFL parlay picks to make here.

    How to make Week 10 NFL parlays

    The model also jumped on four other NFL matchups where it says the line is way off, including backing an underdog that has a chance to win outright. You can only see the model’s NFL Week 10 best bets and parlay at SportsLine. 

    What are the model’s top Week 10 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 10 NFL best bets from a model on a 151-108 run on its top-rated picks, and find out.



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