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The surging Detroit Lions will visit on the Carolina Panthers on Saturday. The Lions have won three in a row to claw their way back to .500, now sitting at 7-7. Dan Campbell’s team has suddenly figured out how to play defense and is firing on all cylinders on offense. Detroit most recently defeated the Jets, 20-17. The 5-9 Panthers, meanwhile, are fresh off a 24-16 defeat at the hands of the Steelers. It’s been a lost year for Carolina, which has cycled through three quarterbacks, fired a head coach and traded away franchise fixture Christian McCaffrey. The Lions are 2.5-point favorites in the Week 16 NFL odds at Caesars Sportsbook. Which Week 16 NFL lines should you target with your Week 16 NFL bets? Before you make any Week 16 NFL picks or NFL parlays, be sure to see the NFL predictions and betting advice from SportsLine’s proven computer model.
The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 15 of the 2022 NFL season on an incredible 157-113 run on top-rated NFL picks that dates back to the 2017 season.
The model ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is WAY UP.
Now, the model has locked in five confident NFL best bets for Week 16. If you successfully parlay its picks, you’d be looking at a massive payout of around 25-1. You can only see the model’s Week 16 NFL picks at SportsLine.
Top Week 16 NFL picks
After simulating every game 10,000 times, the model is high on the Minnesota Vikings (-3.5) to cover against the New York Giants. The Vikings’ weak pass defense shouldn’t hinder them too much against the Giants.
Minnesota has struggled defending the pass, but the Giants are a near-ideal match. New York is mustering just 179 yards of offense through the air per game, the fifth-worst rate in the NFL. A sizable portion of the Giants’ receiving core is injured, leaving Darius Slayton as Daniel Jones‘ most dangerous target. The beleaguered New York pass-catchers should be able to play above their pay grade against Minnesota, but it’s hard to see them truly torching the Vikings. Minnesota is good enough at stuffing the run to give Saquon Barkley trouble too. That is one reason the Vikings are covering the spread in over 50% of simulations. See which other NFL parlay picks to make here.
How to make Week 16 NFL parlays
The model also jumped on four other NFL matchups where it says the line is way off, including a pair of underdogs that have a chance to win outright. You can only see the model’s NFL Week 16 best bets and parlay at SportsLine.
What are the model’s top Week 16 NFL picks? And which other NFL matchups should you target for a strong 25-1 payout? Visit SportsLine now to see the Week 16 NFL best bets from a model on a 157-113 run on its top-rated picks, and find out.
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